Lack of activity of orally administered clofazimine against intracellular Mycobacterium tuberculosis in whole-blood culture.
نویسندگان
چکیده
The activity of oral clofazimine against intracellular Mycobacterium tuberculosis was compared to that of ofloxacin in healthy volunteers by the use of whole-blood cultures. Clofazimine was inactive whether it was tested alone or combined with other drugs that are used to treat multidrug-resistant tuberculosis, despite a total dose of 2 g. Kanamycin was the most active drug tested.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 48 8 شماره
صفحات -
تاریخ انتشار 2004